Description
Flagyl belongs to the group of anti-infective imidazole derivatives.
What it is used
for This medicine is indicated for the treatment of:
Amoebiasis (an infectious disease involving blood-mucous diarrhea);
Urogenital trichomoniasis;
Nonspecific vaginitis;
Giardiasis (infectious disease affecting the small intestine and diarrhea);
Anaerobic infections caused by sensitive anaerobic microorganisms;
Prevention of surgical infections;
Treatment or prevention of infections caused by sensitive anaerobic bacteria after parenteral manipulations.
The recommended dose is:
Vaginitis (inflammation of the vagina) and urethritis (inflammation of the urinary tract) caused by Trichomonas vaginalis:
Adults and adolescents:
2000 mg as a single dose or 200 mg three times daily for 7 days or 400 mg twice daily for 5-7 days.
Your partner should be treated with you even if he or she does not show any clinical symptoms.
Children under 10 years of age: 40 mg / kg orally as a single dose or 15-30 mg / kg / day divided into 2-3 doses for 7 days. Do not exceed 2000 mg / dose
Nonspecific vaginitis
Adults: 500 mg orally twice daily for 7 days. Your partner needs to be treated with you.
Children over 12 years: 400 mg twice daily for 5-7 days or 2000 mg as a single dose.
Amoebiasis
Adults:
1.50 g / day in 3 doses for 7 days
Children over 10 years of age: 400 to 800 mg, three times daily for 5-10 days.
Children 7 to 10 years of age: 200 to 400 mg, three times daily for 5-10 days.
Children 3 to 7 years of age: 100 to 200 mg, four times daily for 5-10 days.
Children 1 to 3 years of age: 100 to 200 mg, three times daily for 5-10 days.
Alternatively, the doses can be expressed according to body weight: 35-50 mg / kg / day in 3 doses for 5-10 days without exceeding 2400 mg / day
Giardiasis
Adults:
750 mg to 1 g / day for 5 consecutive days.
Children
Children over 10 years of age: 2000 mg daily for three days or 400 mg three times daily for 5 days or 500 mg twice daily for 7-10 days.
Children 7 to 10 years of age: 1000 mg daily for three days.
Children 3 to 7 years of age: 600 to 800 mg once daily for 3 days.
Children 1 to 3 years of age: 500 mg once daily for 3 days.
Alternatively expressed in mg / kg body weight:
15-40 mg / kg / day divided into 2-3 doses
Anaerobic infections
Adults: 1 g to 1.50 g / day.
Children:
Children> 8 weeks to 12 years: 20-30 mg / kg / day as a single dose or in 3 divided doses (7.5 mg / kg every 8 hours). The daily dose may be increased to 40 mg / kg according to the severity of the infection. The duration of treatment is usually 7 days. Children <8 weeks: 15 mg / kg as a single daily dose or divided into 2 doses (7.5 mg / kg every 12 hours).
In neonates <40 weeks gestational age, metronidazole accumulation may occur during the first week of life because serum metronidazole concentrations should be monitored preferably after a few days of treatment.
Eradication of Helicobacter pylori in pediatric patients As part of combination therapy, 20 mg / kg / day. Do not exceed 500 mg twice daily for 7 to 14 days. Take into account the official recommendations regarding the proper use of antibacterial agents before initiating therapy.
